Exosomal microRNA-139-5p from mesenchymal stem cells accelerates trophoblast cell invasion and migration by motivation of the ERK/MMP-2 pathway via downregulation of protein tyrosine phosphatase
Huijie Liu, Fang Wang, Ying Zhang, Yanling Xing, Qian Wang
Journal：JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
IF：1.39
DOI：10.1111/jog.14495
PMID：
Published：2020-09-17
research field：分子生物学细胞生物学妇产科学
Abstract
Exosomes present essential roles for intercellular interaction via extracellular pathways during systemic dysfunctions, including preeclampsia (PE). Here, we assessed the specific mechanism of mesenchymal stem cells (MSC)‐originated exosomes in PE.
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