KIF11 is upregulated in colorectal cancer and silencing of it impairs tumor growth and sensitizes colorectal cancer cells to oxaliplatin via p53/GSK3β signaling

Journal:NATURE MEDICINE|DOI:10.1038/s41591-021-01645-7|IF:87.24

Conductive coordination nanozyme prodrugs precisely trigger pyroptosis, cuproptosis and ferroptosis for in situ cancer vaccination

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02607-6|IF:81.2

Thromboxane receptor activation in dendritic cells mitigates sepsis by suppressing S100a8/a9-mediated neutrophil recruitment

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02592-w|IF:81.2

Unleashing the potential of bimetallic nanobomb-mediated STING pathway to enhance bispecific T-cell engager against colorectal cancer photo-immunotherapy

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02596-6|IF:81.2

A biosafe mouse model for SARS-CoV-2 infection that more realistically simulates COVID-19 symptoms

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02640-5|IF:81.2

Investigating the effects and underlying mechanisms of glycosylation sites on the immunogenicity of COVID-19 vaccines

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02751-z|IF:81.2

Disrupting SOX2 self-association and condensate formation to overcome chemotherapeutic drug resistance in lung squamous cell carcinoma

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02696-3|IF:81.2

BMX inhibition overcomes small cell lung cancer chemoresistance by stabilizing E2F1 via ERK1/2-Cyclin D1/CDK4/6 axis

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02644-1|IF:81.2

Multi-Omics Profiling of Long Noncoding RNAs in Clear Cell Renal Cell Carcinoma for Characterization and Clinical Applications

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02573-z|IF:81.2

IL-5 CAR-T cell therapy induces effective remission in hypereosinophilic disorders

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02766-6|IF:81.2

Zinc finger protein 544 promotes hepatocellular carcinoma by generating an immunosuppressive tumor microenvironment

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02701-9|IF:81.2

rFgl2-treated CD32b+M2 macrophages effectively inhibits cardiac transplant rejection in mice

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02765-7|IF:81.2

Peroxidase-Enriched Extracellular Vesicles from Ginkgo biloba Ameliorate Acute Lung Injury via ROS Scavenging, M2 Macrophage Polarization and Barrier Protection

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02685-6|IF:81.2

Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia

Journal:NATURE|DOI:10.1038/s41586-022-05271-2|IF:69.5

32A9, a novel human antibody for designing an immunotoxin and CAR-T cells against glypican-3 in hepatocellular carcinoma

Journal:NATURE|DOI:10.1038/s41586-022-05529-9|IF:69.5

Metformin attenuated sepsis-associated liver injury and inflammatory response in aged mice

Journal:NATURE|DOI:10.1038/s41586-022-04719-9|IF:69.5

Dose optimization of intrathecal administration of human umbilical cord mesenchymal stem cells for the treatment of subacute incomplete spinal cord injury

Journal:NATURE|DOI:10.1038/s41586-022-05030-3|IF:69.5

Circular RNA circGlis3 protects against islet β-cell dysfunction and apoptosis in obesity

Journal:NATURE|DOI:10.1038/s41586-022-05006-3|IF:69.5

Elevated transcription and glycosylation of B3GNT5 promotes breast cancer aggressiveness

Journal:NATURE|DOI:10.1038/s41586-022-04671-8|IF:69.5

MiR-99b-5p Attenuates Adipogenesis by Targeting SCD1 and Lpin1 in 3T3-L1 Cells

Journal:NATURE BIOTECHNOLOGY|DOI:10.1038/s41587-021-01112-1|IF:68.16