[ 1 ]NLR surveillance of pathogen interference with hormone receptors induces immunity

[ 2 ]Olfactory sensory experience regulates gliomagenesis via neuronal IGF1

[ 3 ]Brown-fat-mediated tumour suppression by cold-altered global metabolism

[ 4 ]Opioid-induced fragile-like regulatory T cells contribute to withdrawal

[ 5 ]A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin

[ 6 ]Cholesterylation of Smoothened is a calcium-accelerated autoreaction involving an intramolecular ester intermediate

[ 7 ]Long non-coding RNA LINC00680 functions as a ceRNA to promote esophageal squamous cell carcinoma progression through the miR-423-5p/PAK6 axis

[ 8 ]Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

[ 9 ]Biomimetic Design of Artificial Hybrid Nanocells for Boosted Vascular Regeneration in Ischemic Tissues

[ 10 ]Comprehensive Analysis of Fibroblast Activation Protein (FAP) Expression in Interstitial Lung Diseases (ILDs)

[ 11 ]Cancer cell-derived exosomal circUSP7 induces CD8+ T cell dysfunction and anti-PD1 resistance by regulating the miR-934/SHP2 axis in NSCLC

[ 12 ]Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal

[ 13 ]The OsFTIP6-OsHB22-OsMYBR57 module regulates drought response in rice

[ 14 ]PD-1 signalling defines and protects leukaemic stem cells from T cell receptor-induced cell death in T cell acute lymphoblastic leukaemia

[ 15 ]A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model

[ 16 ]N4-acetylcytidine regulates the replication and pathogenicity of enterovirus 71

[ 17 ]KLF4 inhibits early neural differentiation of ESCs by coordinating specific 3D chromatin structure

[ 18 ]Anti-alcoholism drug disulfiram for targeting glioma energy metabolism using BBB-penetrating delivery of fixed-dose combination

[ 19 ]Fabrication, bacteriostasis and osteointegration properties researches of the additively-manufactured porous tantalum scaffolds loading vancomycin

[ 20 ]RORγt+ APCs require a distinct cis-regulatory element to instruct tolerance to dietary antigens

[ 21 ]Cholinergic Neuron Targeting Nanosystem Delivering Hybrid Peptide for Combinatorial Mitochondrial Therapy in Alzheimer’s Disease

[ 22 ]Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8+/− mouse model of ASD-like behavior

[ 23 ]The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling

[ 24 ]Identification of oleoylethanolamide as an endogenous ligand for HIF-3α

[ 25 ]High-resolution silkworm pan-genome provides genetic insights into artificial selection and ecological adaptation

[ 26 ]Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells

[ 27 ]IL6 supports long-term expansion of hepatocytes in vitro

[ 28 ]Independently evolved viral effectors convergently suppress DELLA protein SLR1-mediated broad-spectrum antiviral immunity in rice

[ 29 ]PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells

[ 30 ]Conscription of Immune Cells by Light-Activatable Silencing NK-Derived Exosome (LASNEO) for Synergetic Tumor Eradication

[ 31 ]Functionalized Macrophage Exosomes with Panobinostat and PPM1D-siRNA for Diffuse Intrinsic Pontine Gliomas Therapy

[ 32 ]Group 3 Innate Lymphoid Cells Protect the Host from the Uropathogenic Escherichia coli Infection in the Bladder

[ 33 ]TGM2-mediated serotonylation of GPX4 confers ferroptosis resistance to promote gastric tumorigenesis

[ 34 ]Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis

[ 35 ]Colon-Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora

[ 36 ]CeO2 nanohybrid as a synergist for insecticide resistance management

[ 37 ]Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO

[ 38 ]Neuraminidase 1 promotes renal fibrosis development in male mice

[ 39 ]Inhibition of ALKBH5 attenuates I/R-induced renal injury in male mice by promoting Ccl28 m6A modification and increasing Treg recruitment

[ 40 ]Nucleus accumbens circuit disinhibits lateral hypothalamus glutamatergic neurons contributing to morphine withdrawal memory in male mice

[ 41 ]Stringent response ensures the timely adaptation of bacterial growth to nutrient downshift

[ 42 ]N6-methyladenosine-modified DBT alleviates lipid accumulation and inhibits tumor progression in clear cell renal cell carcinoma through the ANXA2/YAP axis-regulated Hippo pathway

[ 43 ]Global mapping of circRNA-target RNA interactions reveal P-body-mediated translational repression

[ 44 ]Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation

[ 45 ]Glycolysis drives STING signaling to facilitate dendritic cell antitumor function

[ 46 ]A YAP/TAZ-CD54 axis is required for CXCR2−CD44− tumor-specific neutrophils to suppress gastric cancer

[ 47 ]Ru(II)-modified TiO2 nanoparticles for hypoxia-adaptive photo-immunotherapy of oral squamous cell carcinoma

[ 48 ]Modulating cancer-stroma crosstalk by a nanoparticle-based photodynamic method to pave the way for subsequent therapies

[ 49 ]Collaborative Design of MgO/FeOx Nanosheets on Titanium: Combining Therapy with Regeneration

[ 50 ]A Human-Specific De Novo Gene Promotes Cortical Expansion and Folding

[ 51 ]Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy

[ 52 ]Oral zero-valent-molybdenum nanodots for inflammatory bowel disease therapy

[ 53 ]Gene interfered-ferroptosis therapy for cancers

[ 54 ]A longitudinal sampling study of transcriptomic and epigenetic profiles in patients with thrombocytopenia syndrome

[ 55 ]A novel active transposon creates allelic variation through altered translation rate to influence protein abundance

[ 56 ]The deubiquitinating enzyme 13 retards non-alcoholic steatohepatitis via blocking inactive rhomboid protein 2-dependent pathway

[ 57 ]Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration

[ 58 ]METTL16-mediated m6A modification of MSMO1 modulates cholesterol metabolism and activates MAPK-p38/NF-κB signaling in colorectal cancer

[ 59 ]Multi-scale analysis of nickel ion tolerance mechanism for thermophilic Sulfobacillus thermosulfidooxidans in bioleaching

[ 60 ]Boron contributes to excessive aluminum tolerance in trifoliate orange (Poncirus trifoliata (L.) Raf.) by inhibiting cell wall deposition and promoting vacuole compartmentation

[ 61 ]Bacillus coagulans XY2 ameliorates copper-induced toxicity by bioadsorption, gut microbiota and lipid metabolism regulation

[ 62 ]Characterizing the obesogenic and fatty liver-inducing effects of Acetyl tributyl citrate (ATBC) plasticizer using both in vivo and in vitro models

[ 63 ]Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

[ 64 ]Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer

[ 65 ]Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism or systemic lipolysis in rat

[ 66 ]Identification of TaGL1-B1 gene controlling grain length through regulation of jasmonic acid in common wheat

[ 67 ]A natural promoter variation of SlBBX31 confers enhanced cold tolerance during tomato domestication

[ 68 ]A nitrogen fixing symbiosis-specific pathway required for legume flowering

[ 69 ]Using Fe biofortification strategies to reduce both Ni concentration and oral bioavailability for rice with high Ni

[ 70 ]The gut microbiome promotes arsenic metabolism and alleviates the metabolic disorder for their mammal host under arsenic exposure

[ 71 ]Effects of various Fe compounds on the bioavailability of Pb contained in orally ingested soils in mice: Mechanistic insights and health implications

[ 72 ]Single-cell transcriptome atlas reveals developmental trajectories and a novel metabolic pathway of catechin esters in tea leaves

[ 73 ]Engineering of efficiency-enhanced Cas9 and base editors with improved gene therapy efficacies

[ 74 ]MaNAC029 modulates ethylene biosynthesis and fruit quality and undergoes MaXB3-mediated proteasomal degradation during banana ripening

[ 75 ]Sweet Potato Gene Clusters Control Anthocyanin Biosynthesis and Leaf Morphology

[ 76 ]Local immune dysregulation and subsequent inflammatory response contribute to pulmonary edema caused by Enterovirus infection in mice

[ 77 ]Selective sorting and secretion of hY4 RNA fragments into extracellular vesicles mediated by methylated YBX1 to promote lung cancer progression

[ 78 ]A novel protein encoded by circHNRNPU promotes multiple myeloma progression by regulating the bone marrow microenvironment and alternative splicing

[ 79 ]Targeting ZFP64/GAL-1 axis promotes therapeutic effect of nab-paclitaxel and reverses immunosuppressive microenvironment in gastric cancer

[ 80 ]CircSCAP interacts with SF3A3 to inhibit the malignance of non-small cell lung cancer by activating p53 signaling

[ 81 ]Tetrahedron supported CRISPR/Cas13a cleavage for electrochemical detection of circular RNA in bladder cancer

[ 82 ]Precise gene delivery systems with detachable albumin shell remodeling dysfunctional microglia by TREM2 for treatment of Alzheimer's disease

[ 83 ]HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3

[ 84 ]CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis

[ 85 ]The tetratricopeptide repeat protein OsTPR075 promotes heading by regulating florigen transport in rice

[ 86 ]The tomato OST1–VOZ1 module regulates drought-mediated flowering

[ 87 ]The type-B response regulators ARR10, ARR12, and ARR18 specify the central cell in Arabidopsis

[ 88 ]Competitive Binding of UBA52 and HOPX Modulates β-catenin Stability in Colorectal Cancer in the Context of High-Iron Intake

[ 89 ]AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages

[ 90 ]Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation

[ 91 ]Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents

[ 92 ]UBR5 promotes tumor immune evasion through enhancing IFN-γ-induced PDL1 transcription in triple negative breast cancer.

[ 93 ]HBx represses WDR77 to enhance HBV replication by DDB1-mediated WDR77 degradation in the liver

[ 94 ]Activating AhR alleviates cognitive deficits of Alzheimer's disease model mice by upregulating endogenous Aβ catabolic enzyme Neprilysin

[ 95 ]hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9

[ 96 ]Targeted downregulation of HIF-1α for restraining circulating tumor microemboli mediated metastasis

[ 97 ]Promotion of Bladder Cancer Cell Metastasis by 2-Mercaptobenzothiazole via Its Activation of Aryl Hydrocarbon Receptor Transcription: Molecular Dynamics Simulations, Cell-Based Assays, and Machine Learning-Driven Prediction

[ 98 ]Receptor-like cytoplasmic kinases PBL34/35/36 are required for CLE peptide-mediated signaling to maintain shoot apical meristem and root apical meristem homeostasis in Arabidopsis

[ 99 ]Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy

[ 100 ]A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension