Escitalopram Oxalate ((S)-Citalopram oxalate, (S)-(+)-Citalopram oxalate)，又称依他普仑草酸盐或草酸右旋西酞普兰，是外消旋Citalopram的S-对映体，是血清素(5-HT)再摄取抑制剂(SSRI)，K_i为0.89 nM，对去甲肾上腺素和多巴胺的再吸收影响很小，可用于抑郁症治疗。

参考文献

1.Zhang, P, et al. Structure-activity relationships for a novel series of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbon itrile) analogues at monoamine transporters. J Med Chem. 2010 Aug 26;53(16):6112-21.

2.Pastoor, D. and J. Gobburu, Clinical pharmacology review of escitalopram for the treatment of depression. Expert Opin Drug Metab Toxicol. 2014 Jan;10(1):121-8.

3.Wu C , et al. Escitalopram alleviates stress-induced Alzheimer's disease-like tau pathologies and cognitive deficits by reducing hypothalamic-pituitary-adrenal axis reactivity and insulin/GSK-3β signal pathway activity. Neurobiol Aging. 2018 Jul;67:137-147.

4.Cirrito JR, et al. Effect of escitalopram on Aβ levels and plaque load in an Alzheimer mouse model. Neurology. 2020 Nov 10;95(19):e2666-e2674.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。