Tangeretin（又名桔皮素，橘皮素，Tangeritin, NSC53909, NSC-53909, NSC618905, NSC-618905）是一种存在于柑橘类水果皮中的黄酮类化合物，也是有效的Notch-1抑制剂。研究表明Tangeretin可抑制几种癌细胞增殖，在抗癌、抗炎及神经保护方面可发挥作用。

参考文献

[1]. Zheng J, et al. Tangeretin inhibits hepatocellular carcinoma proliferation and migration by promoting autophagy-related BECLIN1. Cancer Manag Res. 2019 Jun 6; 11:5231-5242.

[2]. Li M, Zhao Y, et al. Tangeretin attenuates lipopolysaccharide-induced acute lung injury through Notch signaling pathway via suppressing Th17 cell response in mice. Microb Pathog. 2020 Jan; 138:103826.

[3]. Xu S, Kong YG, et al. Tangeretin promotes regulatory T cell differentiation by inhibiting Notch1/Jagged1 signaling in allergic rhinitis. Int Immunopharmacol. 2019 Jul; 72:402-412.

[4]. Lin JJ, Huang CC, et al. Proteomics Analysis of Tangeretin-Induced Apoptosis through Mitochondrial Dysfunction in Bladder Cancer Cells. Int J Mol Sci. 2019 Feb 26;20(5):1017. 

[5]. Liu Y, et al. Tangeretin inhibits streptozotocin-induced cell apoptosis via regulating NF-κB pathway in INS-1 cells. J Cell Biochem. 2019 Mar;120(3):3286-3293. 

冰袋运输。粉末直接保存于-20℃，有效期2年。建议分装后-20℃避光保存，避免反复冻融。