Swainsonine 苦马豆碱
产品介绍
Swainsonine是一种天然吲哚里西啶类生物碱,作为可逆性α-甘露糖苷酶抑制剂,能诱导细胞凋亡及G2/M期周期阻滞,并表现出抗肿瘤活性。
产品性质
产品特色
/
存储条件
-25~-15℃避光保存,有效期3年。
COA
已发表文献
[1] Sun L, Jin X, Xie L, Xu G, Cui Y, Chen Z. Swainsonine represses glioma cell proliferation, migration and invasion by reduction of miR-92a expression. BMC Cancer. 2019 Mar 19;19(1):247. doi: 10.1186/s12885-019-5425-7. Retraction in: BMC Cancer. 2024 Feb 29;24(1):275. doi: 10.1186/s12885-024-12034-x. PMID: 30890138; PMCID: PMC6425678.
[2]Santos FM, Latorre AO, Hueza IM, Sanches DS, Lippi LL, Gardner DR, Spinosa HS. Increased antitumor efficacy by the combined administration of swainsonine and cisplatin in vivo. Phytomedicine. 2011 Sep 15;18(12):1096-101. doi: 10.1016/j.phymed.2011.06.005. Epub 2011 Jul 16. PMID: 21763115.
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