[ 1 ]A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin

[ 2 ]Bioinspired, Mitochondria-Targeted Single-Atom Nanozyme Enhances Bone Regeneration by Reprogramming Stem Cell Energy Metabolism​

[ 3 ]Time-of-Day Defines the Risk of Thermally Abused Frying Oil to Renal Injury by Modulating the Diurnal Dynamics of Oxylipins

[ 4 ]A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model

[ 5 ]Immuno-Training Remodeled Vascular Microenvironment via Peptide-Functionalized Hydrogel Microspheres for Neural Repair

[ 6 ]Identification of a Bioactive Domain in Type II Collagen That Promotes Bone Repair via EGFR Signaling

[ 7 ]An engineered lamellar bone mimicking full-scale hierarchical architecture for bone regeneration

[ 8 ]3D printed pore morphology mediates bone marrow stem cell behaviors via RhoA/ROCK2 signaling pathway for accelerating bone regeneration

[ 9 ]A non-enzymatic function of neuraminidase 1 restrains hepatic glucagon response in mice

[ 10 ]Cholinergic Neuron Targeting Nanosystem Delivering Hybrid Peptide for Combinatorial Mitochondrial Therapy in Alzheimer’s Disease

[ 11 ]Anionic nanoplastic exposure induces endothelial leakiness

[ 12 ]Balancing Microthrombosis and Inflammation via Injectable Protein Hydrogel for Inflammatory Bowel Disease

[ 13 ]Colon-Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora

[ 14 ]Modular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field

[ 15 ]H2O2 sulfenylates GRF8 to facilitate jasmonate signaling by relieving MYC2 inhibition in Arabidopsis

[ 16 ]DNA Framework-Encoded Digital Recorder for Bacterial Discrimination

[ 17 ]In Situ Redox-Omics Decoding of Nanoparticle–Protein Corona Interactions Drives the Mitochondrial Metabolic-Immunological Mechanism in Microglia

[ 18 ]Meningeal Lymphatic System-Driven Nanodelivery Unlocks Ursolic Acid’s Pleiotropic Benefits To Optimize Multiple Sclerosis Treatment

[ 19 ]Treg-γδ T cell axis determines sexual dimorphism in hepatocarcinogenesis

[ 20 ]Vacancy defect-induced electron homing breaks phosphodiester bonds for RNA depletion-driven cancer therapy

[ 21 ]Oral zero-valent-molybdenum nanodots for inflammatory bowel disease therapy

[ 22 ]Omega-based mini prime- and base-editing systems in Escherichia coli

[ 23 ]Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1α/NF-κB feedback pathway to inhibit liver fibrosis

[ 24 ]Synergistic action of the gut microbiota in environmental RNA interference in a leaf beetle

[ 25 ]Bone-derived MSCs encapsulated in alginate hydrogel prevent collagen-induced arthritis in mice through the activation of adenosine A2A/2B receptors in tolerogenic dendritic cells

[ 26 ]Polystyrene nanoparticle exposure supports ROS-NLRP3 axis-dependent DNA-NET to promote liver inflammation

[ 27 ]Efficient disinfection of SARS-CoV-2-like coronavirus, pseudotyped SARS-CoV-2 and other coronaviruses using cold plasma induces spike protein damage

[ 28 ]Phocaeicola coprophilus-Derived 6-Methyluracil Attenuates Radiation-Induced Intestinal Fibrosis by Suppressing the IDO1-Kynurenine-AHR Axis

[ 29 ]N4-acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

[ 30 ]Targeting UXS1-Dependent Glucuronate Detoxification Potentiates Metformin's Anti-Tumor Efficacy in Lung Adenocarcinoma

[ 31 ]Super-Enhancer-Driven SOX4/SMAD3 Mediate Membrane Remodeling by Regulating Phospholipid Metabolism to Accelerate Leukemia Progression

[ 32 ]SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis

[ 33 ]Bacterial drug-resistance and viability phenotyping upon disinfectant exposure revealed by single-nucleotide resolved-allele specific isothermal RNA amplification

[ 34 ]Sulfenylation of ENOLASE2 facilitates H2O2-conferred freezing tolerance in Arabidopsis

[ 35 ]Super-enhancer-driven TCF4 orchestrates neuroblastoma metastasis by sphingolipid-dependent membrane remodeling and ITGB1-FAK activation

[ 36 ]Carrier-free dual-drug nanoplatforms cooperatively remodel macrophage and VSMC fate specifications for treating abdominal aortic aneurysm

[ 37 ]An epigenetically enhanced whole-cell vaccine in a stimulatory hydrogel for robust antitumor immunity

[ 38 ]Janus silk-based patch with temporary adhesion for inflammatory mediators removal in corneal alkali burn treatment

[ 39 ]Local immune dysregulation and subsequent inflammatory response contribute to pulmonary edema caused by Enterovirus infection in mice

[ 40 ]Selective sorting and secretion of hY4 RNA fragments into extracellular vesicles mediated by methylated YBX1 to promote lung cancer progression

[ 41 ]Therapeutic translation of traditional Chinese medicine Huangqi derived exosome like nanoparticles: targeting prostate cancer through ferroptosis activation, immune reprogramming, and microbiome modulation

[ 42 ]RSV temporally reprograms apoptosis and pyroptosis to balance immune evasion and replication

[ 43 ]R-loop processing via REXO4-RNaseH1–mediated endo- and exo-cleavage coupling mode prevents genome instability and antitumor immunity

[ 44 ]Precise gene delivery systems with detachable albumin shell remodeling dysfunctional microglia by TREM2 for treatment of Alzheimer's disease

[ 45 ]HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3

[ 46 ]A novel mRNA nanovaccine with dual immunoregulation ameliorates rheumatoid arthritis and associated pneumonia

[ 47 ]Histamine activates HinK to promote the virulence of Pseudomonas aeruginosa

[ 48 ]HDAC7-Induced Epigenetic Repression Modulates ATF3 Functional Plasticity in Colorectal Cancer Pathogenesis

[ 49 ]Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis

[ 50 ]MtNPF6.5 mediates chloride uptake and nitrate preference in Medicago roots

[ 51 ]M2 microglial small extracellular vesicles reduce glial scar formation via the miR-124/STAT3 pathway after ischemic stroke in mice

[ 52 ]CASB: a concanavalin A-based sample barcoding strategy for single-cell sequencing

[ 53 ]Genipin induces liver injury by disrupting the CPS1-regulated urea cycle and redox homeostasis

[ 54 ]MRI-guided diagnosis and dual-pathway neuroprotection in ischemic stroke via PDA-engineered apple exosome-like nanoparticles

[ 55 ]β-Ionone causes endocrine disruption, hyperpigmentation and hypoactivity in zebrafish early life stages

[ 56 ]Polychlorinated biphenyl quinone induces immunotoxicity via lymphocytes apoptosis and Th1-Th2 cell imbalance in C57BL/6 mice

[ 57 ]Fecal transplantation from young zebrafish donors efficiently ameliorates the lipid metabolism disorder of aged recipients exposed to perfluorobutanesulfonate

[ 58 ]Testicular toxicity of bisphenol compounds: Homeostasis disruption of cholesterol/testosterone via PPARα activation

[ 59 ]RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

[ 60 ]Synergistic ferroptosis and macrophage re-polarization using engineering exosome-mimic M1 nanovesicles for cancer metastasis suppression

[ 61 ]DcH3.3 and DcNAC1 Regulate the Expression of UGT73A93 Involved in the Changes in Flower Colour and Fungal Resistance in Carnation

[ 62 ]CCS facilitates the progression of ovarian cancer by suppressing ferroptotic cell death via the modulation of p53-mediated expression of SLC7A11 and GPX4

[ 63 ]Transplastomic tomatoes expressing double-stranded RNA against a conserved gene are efficiently protected from multiple spider mites

[ 64 ]Lipid disturbance and neuroinflammation contribute to Aflatoxin B1-linked Parkinsonism: an in vitro, in vivo, and Parkinsonism patients’ integrating evidence

[ 65 ]Selective ischemic-hemisphere targeting Ginkgolide B liposomes with improved solubility and therapeutic efficacy for cerebral ischemia-reperfusion injury

[ 66 ]miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways

[ 67 ]Single-cell Deciphering of the Progression Trajectories of the Tumor Ecosystem in Laryngeal Squamous Cell Carcinoma

[ 68 ]Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis

[ 69 ]Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy

[ 70 ]HULC targets the IGF1R–PI3K-AKT axis in trans to promote breast cancer metastasis and cisplatin resistance

[ 71 ]Combining adoptive NK cell infusion with a dopamine-releasing peptide reduces senescent cells in aged mice

[ 72 ]A joint strategy comprising melatonin and 3-methyladenine to concurrently stimulate biomass and astaxanthin hyperaccumulation by Haematococcus pluvialis

[ 73 ]Malic enzyme 1 contributes to tumorigenesis and lenvatinib resistance in hepatocellular carcinoma via FSP1-dependent ferroptosis evasion

[ 74 ]M2 macrophages promote lymphatic metastasis by regulating PKM2 nuclear translocation in triple-negative breast cancer

[ 75 ]Zinc-Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

[ 76 ]ISGylation prevents autophagic degradation of STING and promotes antitumor immunity in lung cancer

[ 77 ]Combination of a nanocarrier delivery system with genetic manipulation further improves pesticide efficiency: a case study with chlorfenapyr

[ 78 ]Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome

[ 79 ]LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity

[ 80 ]Deubiquitinase OTULIN dampens RIG-I-dependent antiviral signaling by removing linear ubiquitination from TRAF6

[ 81 ]A Pseudomonas sp. strain uniquely degrades PAHs and heterocyclic derivatives via lateral dioxygenation pathways

[ 82 ]Nitrospira-Driven partial Denitrification: Kinetics, Mechanisms, and synergistic potential with anammox

[ 83 ]CIGAR-seq, a CRISPR/Cas-based method for unbiased screening of novel mRNA modification regulators

[ 84 ]CAPNS1/Dicer feedback loop facilitates glycolysis, proliferation, and metastasis in hepatocellular carcinoma cells by inhibiting the maturation of MicroRNA pool

[ 85 ]Lnc90386 Sponges miR-33-5p to Mediate Mycoplasma gallisepticum-Induced Inflammation and Apoptosis in Chickens via the JNK Pathway

[ 86 ]Identification of Immune-Related Gene Signature and Prediction of CeRNA Network in Active Ulcerative Colitis

[ 87 ]Analysis of Tumor Glycosylation Characteristics and Implications for Immune Checkpoint Inhibitor's Efficacy for Breast Cancer

[ 88 ]Landscape of prognosis and immunotherapy responsiveness under tumor glycosylation-related lncRNA patterns in breast cancer.

[ 89 ]Lnc90386 Sponges miR-33-5p to Mediate Mycoplasma gallisepticum-Induced Inflammation and Apoptosis in Chickens via the JNK Pathway

[ 90 ]Human ESC-derived immunity- and matrix- regulatory cells ameliorated white matter damage and vascular cognitive impairment in rats subjected to chronic cerebral hypoperfusion

[ 91 ]Circular RNA hsa_circ_0083756 promotes intervertebral disc degeneration by sponging miR-558 and regulating TREM1 expression

[ 92 ]KSR2-14–3-3ζ complex serves as a biomarker and potential therapeutic target in sorafenib-resistant hepatocellular carcinoma

[ 93 ]Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication

[ 94 ]Investigate the interacting proteins and target site motifs of Smad4a/b/c/d transcription factors in zebrafish

[ 95 ]A natural bioadhesive derived from Eucommia ulmoides gum for enhanced wound repair

[ 96 ]A paradigm shift in diabetic wound care: Multifunctional silk fibroin-glycidyl methacrylate hydrogels delivering stem cell and immune cell secretome

[ 97 ]Wnt/β-catenin signaling mediates the abnormal osteogenic and adipogenic capabilities of bone marrow mesenchymal stem cells from chronic graft-versus-host disease patients

[ 98 ]Effects of short-chain fatty acids in inhibiting HDAC and activating p38 MAPK are critical for promoting B10 cell generation and function

[ 99 ]3D printed PCL/SrHA scaffold for enhanced bone regeneration

[ 100 ]Phosphorus magnesium fiber regulates macrophage polarization through TRPM7 to accelerate wound healing