造血干细胞培养细胞因子选购指南

10046

2025-12-25

造血干细胞是存在于骨髓、脐带血等造血组织中的成体干细胞，兼具高度自我更新能力与多向分化潜能既能通过分裂维持自身种群数量稳定，又能分化为红细胞、白细胞、血小板等所有血液细胞类型，还可迁移至外周血参与造血调控。

造血干细胞的干性维持、分化及造血稳态均依赖细胞因子调控：SCF、TPO保持干性，GM-CSF、EPO等引导分化为各类血细胞，IL-3、IL-6调节增殖存活；临床中G-CSF可动员造血干细胞进入外周血以便采集、SCF能体外扩增造血干细胞提升移植效率，细胞因子是造血干细胞功能调控与相关疾病治疗的核心。

参与造血干细胞分化的细胞因子示意图

HSC培养细胞因子推荐

细胞因子	货号	种属	表达宿主
IL-1α	90100ES	Human	E.coli
IL-1β	90277ES	Human	HEK293
IL-2	90267ES	Human	CHO
IL-3	90104ES	Human	E.coli
IL-4	90105ES	Human	E.coli
IL-5	90279ES	Human	HEK293
IL-6	90107ES	Human	E.coli
IL-7	90188ES	Human	E.coli
IL-10	90109ES	Human	E.coli
IL-11	90282ES	Human	HEK293
IL-12	90262ES	Human	CHO
IL-15	90113ES	Human	E.coli
TGF-β1	91701ES	Human/Mouse/Rat	HEK293
TGF-β3	91705ES	Human	CHO
SCF	92251ES	Human	E.coli
EPO	92804ES	Human	HEK293
TPO	92261ES	Human	HEK293
FLT3L	92259ES	Human	E.coli
SDF-1	90914ES	Human	E.coli
TNF-α	90601ES	Human	E.coli
CD40L	90606ES	Human	E.coli
BAFF	90604ES	Human	HEK293
G-CSF	91117ES	Human	HEK293
GM-CSF	91102ES	Human	E.coli
M-CSF	91103ES	Human	HEK293

产品验证数据展示：

高纯度

Human IL-1β

Human IL-3

Human EPO

High-purity: ≥ 95% as determined by SDS-PAGE and SEC-HPLC.

高生物活性

Human IL-1β

Human IL-3

Human EPO

High-activity: The ED₅₀ as determined by a cell proliferation assay using D10.G4.1 is less than 20 pg/mL. The specific activity of Human IL-1beta Protein is > 5.0 × 10⁷ IU/mg.

High-activity: The ED₅₀as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng/mL. The specific activity of > 1.0 × 10⁷ IU/mg.

High-activity: The ED₅₀ as determined by a cell proliferation assay using human TF‑1 erythroleukemic cells is 0.4 ‑ 1 ng/mL.

高稳定性

Human IL-3

Accelerated Stability： Cell proliferation assay of Human TF-1 cells shows that Human IL-3 protein is stable at 37℃ for 48 hours after reconstitution.

Human IL-3