Donepezil Hydrochloride (E2020, Donepezil HCl)，又称盐酸多奈哌齐，是乙酰胆碱酯酶AChE选择性抑制剂，临床上用于治疗阿尔兹海默症(AD)，可改善轻度至中度严重的AD病人的认知功能。

参考文献

[1] H Ogura, et al. Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol. 2000 Oct;22(8):609-13.

[2] Snape MF, et al. A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066. Neuropharmacology. 1999 Jan;38(1):181-93.

[3] Huang ZH, et al. Donepezil protects endothelial cells against hydrogen peroxide-induced cell injury. CNS Neurosci Ther. 2012 Feb;18(2):185-7.

[4] Shin CY, et al. The Effects of Donepezil, an Acetylcholinesterase Inhibitor, on Impaired Learning and Memory in Rodents. Biomol Ther (Seoul). 2018 May 1;26(3):274-281.

冰袋运输。粉末直接保存于-25~-15℃，有效期3年。建议溶解分装后于-25~-15℃干燥保存，避免反复冻融。