Fluoxetine hydrochloride盐酸氟西汀
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53270ES50
50 mg
现货
¥ 525.00
53270ES60
100 mg
现货
¥ 795.00
53270ES72
250 mg
现货
¥ 1375.00
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Fluoxetine hydrochloride (Fluoxetine HCl, LY-110140, LY110140, Lilly110140, Lilly-110140),也称盐酸氟西汀,商品名百优解,是一种抗抑郁药,常用于治疗各种抑郁性精神障碍,包括轻性或重性抑郁症、双相情感性精神障碍的抑郁症,及抑郁性神经症。盐酸氟西汀是一种选择性血清素重吸收抑制剂,是突触前5-羟色胺再摄取抑制剂,抑制神经元从突触间隙中摄取5-羟色胺。
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参考文献
- Malberg JE, et al. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology. 2003 Sep;28(9):1562-71.
- Kodama M, et al. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat. Biol Psychiatry. 2004 Oct 15;56(8):570-80.
- Wang JW, et al. Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. J Neurosci. 2008 Feb 6;28(6):1374-84.
- Bymaster FP, et al. Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Psychopharmacology (Berl). 2002 Apr;160(4):353-61.
- Zhang W, et al. Synergistic effects of olanzapine and other antipsychotic agents in combination with fluoxetine on norepinephrine and dopamine release in rat prefrontal cortex. Neuropsychopharmacology. 2000 Sep;23(3):250-62.
存储条件
冰袋运输。粉末直接保存于-20℃,有效期3年。建议分装后-20℃干燥保存,避免反复冻融。
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