Dorsomorphin 2HCl盐酸多索啡 可逆AMPK抑制剂|Dorsomorphin dihydrochloride|CAS 1219168-18-9（53010ES）

Dorsomorphin dihydrochloride (Dorsomorphin 2HCl)是一种ATP竞争型的选择性的高效可逆的AMPK抑制剂，其体外Ki值为109 nM，可诱导肿瘤细胞的细胞自噬。

参考文献

[1]. Saito S, et al. Compound C prevents the unfolded protein response during glucose deprivation through a mechanism independent of AMPK and BMP signaling. PLoS One. 2012;7(9):e45845.

[2]. Yu PB, et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 2008 Jan;4(1):33-41.

[3]. Dasgupta B, et al. Compound C/Dorsomorphin: Its Use and Misuse as an AMPK Inhibitor. Methods Mol Biol. 2018;1732:195-202.

冰袋运输。粉末直接保存于-20℃，有效期2年。建议分装后-20℃干燥保存，避免反复冻融。