Hh Pathway-IN-1是一种Hedgehog (Hh)通路抑制剂,能强效拮抗Gli。它可抑制Hh通路功能,且不抑制Wnt信号传导。该化合物具有抗增殖活性,并能降低GLI1 mRNA的表达。此外,Hh Pathway-IN-1能够以剂量依赖性的方式抑制克隆形成。

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