Furosemide sodium是口服有效的NKCC（含NKCC1、NKCC2）共转运蛋白抑制剂，同时是GABAA受体亚型选择性拮抗剂（对含α6受体的选择性是α1受体的100倍），主要用作利尿试剂，适用于充血性心力衰竭、高血压和水肿的研究。

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