Bumetanide布美他尼 利尿剂/协同转运蛋白(NKCC)抑制剂|CAS 28395-03-1（54602ES）

Bumetanide，又称布美他尼，是一种氨磺酰基类的利尿剂，用于治疗水肿性疾病。Bumetanide能够抑制Na⁺-K⁺-Cl⁺协同转运蛋白(NKCC)。

参考文献

[1] Lykke K, Töllner K, Feit PW, et al. The search for NKCC1-selective drugs for the treatment of epilepsy: Structure-function relationship of bumetanide and various bumetanide derivatives in inhibiting the human cation-chloride cotransporter NKCC1A. Epilepsy Behav. 2016 Jun;59:42-9. doi: 10.1016/j.yebeh.2016.03.021(IF:2.378).

[2] O'Donnell ME, Tran L, Lam TI, et al. Bumetanide inhibition of the blood-brain barrier Na-K-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke. J Cereb Blood Flow Metab. 2004 Sep;24(9):1046-56. doi: 10.1097/01.WCB.0000130867.32663.90(IF:6.04).

-25~-15℃保存，有效期3年。