The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target.

高纯度、高活性、低内毒素、高批间一致性

Bis-Tris PAGE

Human IGF1R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Human IGF1R is greater than 90% as determined by SEC-HPLC.

ELISA Data

Immobilized CD221/IGF1R His Tag Protein, Human at 5.0μg/mL (100μL/well) can bind Recombinant Human IGF1 Protein (Fc Tag) with EC50 of 29.25-35.48ng/mL.

-25 ~ -15℃保存，收到货之后有效期1年。
复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。