酒石酸托特罗定（研发代号Kabi-2234, PNU-200583E）是一种有效的毒蕈碱受体拮抗剂，其在体内对膀胱具有显著的组织选择性。
|
英文别名 (English Synonym) |
Tolterodine tartrate |
|
中文名称 (Chinese Name) |
|
|
靶点 (Target) |
Muscarinic Receptor |
|
通路 (Pathway) |
Neuroscience |
|
CAS号 (CAS NO.) |
124937-52-6 |
|
分子式 (Formula) |
C26H37NO7 |
|
分子量 (Molecular Weight) |
475.57 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Nilvebrant L. Tolterodine and its active 5-hydroxymethyl metabolite: pure muscarinic receptor antagonists. Pharmacol Toxicol. 2002 May;90(5):260-7. doi: 10.1034/j.1600-0773.2002.900506.x. PMID: 12076307.[2]Cappon GD, Bush B, Newgreen D, Finch GL, Alper RH. Tolterodine does not affect memory assessed by passive-avoidance response test in mice. Eur J Pharmacol. 2008 Jan 28;579(1-3):225-8. doi: 10.1016/j.ejphar.2007.10.063. Epub 2007 Oct 30. PMID: 18031724.
