Methionine（MRX-1024, D-Methionine）是一种有效的化学保护剂,它通过激活GABAA受体来抑制神经元活性。
|
英文别名 (English Synonym) |
Methionine |
|
中文名称 (Chinese Name) |
D-蛋氨酸；D-甲硫氨酸 |
|
靶点 (Target) |
GABA Receptor |
|
通路 (Pathway) |
Neuronal Signaling |
|
CAS号 (CAS NO.) |
348-67-4 |
|
分子式 (Formula) |
C5H11NO2S |
|
分子量 (Molecular Weight) |
149.21 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于H2O |
-25~-15℃保存，有效期3年
[1] Sooriyaarachchi M, White WM, Narendran A, Gailer J. Chemoprotection by D-methionine against cisplatin-induced side-effects: insight from in vitro studies using human plasma. Metallomics. 2014 Mar,6(3):532-41. doi: 10.1039/c3mt00238a. Epub 2013 Dec 16. PMID: 24337005.[2]Hinduja S, Kraus KS, Manohar S, Salvi RJ. D-methionine protects against cisplatin-induced neurotoxicity in the hippocampus of the adult rat. Neurotox Res. 2015 Apr,27(3):199-204. doi: 10.1007/s12640-014-9503-y. Epub 2014 Dec 9. PMID: 25488710, PMCID: PMC4376112.
