Clozapine N-oxide，又称氯氮平N-氧化物，是抗精神病药物Clozapine的代谢产物，可穿过血脑屏障，是多巴胺受体拮抗剂，也可以激活人毒蕈碱设计受体(DREADDs)。

参考文献

[1] Wess J, Nakajima K, Jain S. Novel designer receptors to probe GPCR signaling and physiology. Trends Pharmacol Sci. 2013 Jul;34(7):385-92. doi: 10.1016/j.tips.2013.04.006(IF:11.523).

[2] Manvich DF, Webster KA, Foster SL, et al. The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice. Sci Rep. 2018 Mar 1;8(1):3840. doi: 10.1038/s41598-018-22116-z(IF:4.011).

-25~-15℃保存，有效期3年。