PF-573228 粘着斑激酶FAK抑制剂/抗血管生成剂|CAS 869288-64-2（54549ES）

PF-573228是粘着斑激酶FAK抑制剂，IC₅₀为4 nM，是抗血管生成剂。

参考文献

[1] Slack-Davis JK, Martin KH, Tilghman RW, et al. Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem. 2007 May 18;282(20):14845-52.  doi: 10.1074/jbc.M606695200(IF:4.106).

[2] Fan H, Guan JL. Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity. J Biol Chem. 2011 May 27;286(21):18573-82. doi: 10.1074/jbc.M110.200717(IF:4.106).

-25~-15℃保存，有效期3年。