Letrozole来曲唑是一种新型有效的芳香酶抑制剂（Aromatase抑制剂，IC₅₀=11.5 nM），属于可逆的非甾体类化合物，能抑制芳香化酶，还能抑制雌激素受体(ER)的表达。

参考文献

[1] Mitropoulou TN, et al. Letrozole as a potent inhibitor of cell proliferation and expression of metalloproteinases (MMP-2 and MMP-9) by human epithelial breast cancer cells. Int J Cancer. 2003 Mar 20;104(2):155-60.

[2] Chen Bian, et al. Aromatase inhibitor letrozole downregulates steroid receptor coactivator-1 in specific brain regions that primarily related to memory, neuroendocrine and integration. The Journal of Steroid Biochemistry and Molecular Biology. May 2014. 141: 37-43.

[3] Lee K, et al. An in vivo model of intratumoural aromatase using aromatase-transfected MCF7 human breast cancer cells. Int J Cancer. 1995 Jul 28;62(3):297-302.

-25~-15℃保存，有效期3年。避光干燥保存，避免反复冻融。