Tacrolimus他克莫司(藤霉素/大环哌喃) 大环内酯类/免疫抑制剂|CAS 104987-11-3（53619ES）

Tacrolimus (FK506, FR900506, Fujimycin, Prograf, FK-506, FR-900506)，又称他克莫司、藤霉素、他克莫斯或大环哌喃，是大环内酯类，是一种免疫抑制剂。在T淋巴细胞中，FK506与FKBP12结合抑制钙调神经磷酸酶介导的信号传导。

参考文献

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4.Okada Y, et al. Tacrolimus ameliorates dextran sulfate sodium-induced colitis in mice: implication of interleukin-1β suppression. Biol Pharm Bull. 2011;34(12):1823-7.

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