Silodosin (KAD 3213, KMD 3213, KAD3213, KMD3213)，又称西罗多辛或赛洛多辛，是可口服的α1-肾上腺素受体拮抗剂，表现出高泌尿选择性，作用于α1A-AR、α1B-AR和α1D-AR的K_i值为0.036 nM、21 nM和2 nM，临床上主要用于治疗治疗良性前列腺肥大，可改善膀胱功能。

参考文献

[1] Maxime Rossi, et al. Silodosin in the treatment of benign prostatic hyperplasia. Drug Des Devel Ther. 2010 Oct 27;4:291-7.

[2] Kawahara T, et al. Silodosin inhibits the growth of bladder cancer cells and enhances the cytotoxic activity of cisplatin via ELK1 inactivation.Am J Cancer Res. 2015 Sep 15;5(10):2959-68.

[3] Villa L, et al. Effects by silodosin on the partially obstructed rat ureter in vivo and on human and rat isolated ureters.Br J Pharmacol. 2013 May;169(1):230-8.

冰袋运输。粉末直接保存于-25~-15℃，有效期3年。建议溶解分装后于-25~-15℃干燥保存，避免反复冻融。