PIK-93 (PIK93)是一种高效的PI4K抑制剂（PI4KIIIβ抑制剂）（IC₅₀=19 nM），选择性地抑制PI4KIIIβ酶以及siRNA介导PI4-酶的下调。PIK93具有抗PV效果，对PV假病毒感染的EC₅₀为0.14 μM。 

参考文献

[1] Arita M, et al. Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity. J Virol. 2011 Mar;85(5):2364-72.

[2] Monet M, et al. Involvement of phosphoinositide 3-kinase and PTEN protein in mechanism of activation of TRPC6 protein in vascular smooth muscle cells. J Biol Chem. 2012 May 18;287(21):17672-81.

[3] Tóth B, et al. Phosphatidylinositol 4-kinase IIIbeta regulates the transport of ceramide between the endoplasmic reticulum and Golgi. J Biol Chem. 2006 Nov 24;281(47):36369-77.

[4] Hsu, N. Y., et al. 2010. Viral reorganization of the secretory pathway generates distinct organelles for RNA replication. Cell 141:799-811.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。