B7-1 is a member of the cell surface immunoglobulin superfamily. CD80 is mainly expressed on the surface of activated B cells, macrophages, dendritic cells and other antigen-presenting cells. B7-1 and B7-2 form co-stimulatory ligands that can interact with the co-stimulatory receptor CD28 expressed on T cells and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4). When interacting with CD28, it is generally used for self-regulation and intercellular binding; When interacting with CTLA-4, it is used to regulate attenuation and cell separation. CD80 plays a role in inducing congenital immune response by activating the NF-κb signaling pathway in macrophages. Therefore, CD80 is considered a promising therapeutic target for autoimmune diseases and various cancers.

高纯度、高活性、低内毒素、高批间一致性

-25 ~ -15℃保存，收到货之后有效期1年。 复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。