Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. The 65 kDa long isoform of human Nectin-2/CD112 (Nectin-2δ) consists of a 329 amino acid (aa) extracellular region (ECD) with three immunoglobulin-like domains, a 21 aa transmembrane segment, and a 157 aa cytoplasmic domain. Within the ECD, human Nectin-2 shares 72% aa sequence identity with mouse Nectin-2. Nectin-2 localizes to adherens junctions between neurons, endothelial cells, epithelial cells, and fibroblasts. Nectin-2 is known to bind pseudorabies virus and herpes simplex virus-2 (HSV-2), but not HSV-1 or poliovirus.
高纯度、高活性、低内毒素、高批间一致性
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Tris-Bis PAGE
-25 ~ -15℃保存，收到货之后有效期1年。 复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。
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