Dexamethasone Acetate醋酸地塞米松
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53278ES76
500 mg
现货
¥ 525.00
53278ES80
1 g
现货
¥ 815.00
53278ES90
5 g
现货
¥ 2015.00
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Dexamethasone Acetate (Dexamethasone 21-acetate, Dexamethasone acetate, NSC 39471, NSC39471),又称醋酸地塞米松,是糖皮质素类甾体化合物,属于类固醇药物,有抗炎和免疫抑制活性。Dexamethasone是白细胞介素受体调节剂,能调节T细胞分化和生长,用于很多炎症和自身免疫病的治疗,例如风湿性关节炎和支气管痉挛。
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参考文献
- LaLone CA, et al. Effects of a glucocorticoid receptor agonist, Dexamethasone, on fathead minnow reproduction, growth, and development. Environ Toxicol Chem. 2012 Mar;31(3):611-22.
- Adcock IM, et al. Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-kappaB and lack of I-kappaB involvement. Br J Pharmacol. 1999 Jun;127(4):1003-11.
- Romero IA, et al. Changes in cytoskeletal and tight junctional proteins correlate with decreased permeability induced by dexamethasone in cultured rat brain endothelial cells. Neurosci Lett. 2003 Jun 26;344(2):112-6.
- Rocksén D, et al. Differential anti-inflammatory and anti-oxidative effects of Dexamethasone and N-acetylcysteine in endotoxin-induced lung inflammation. Clin Exp Immunol. 2000 Nov;122(2):249-56.
- Roussel D, et al. Dexamethasone treatment specifically increases the basal proton conductance of rat liver mitochondria. FEBS Lett. 2003 Apr 24;541(1-3):75-9.
存储条件
冰袋运输。粉末直接保存于-20℃,有效期3年。建议分装后-20℃干燥保存,避免反复冻融。
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