AG-18(AG18/Tyrphostin A23/RG 50810)酪氨酸磷酸化抑制剂23 EGFR激酶抑制剂|CAS 118409-57-7（52720ES）

AG-18(RG-50810; Tyrphostin A23)是EGFR激酶的抑制剂，其IC50为35 μM，阻断酪氨酸的磷酸化及其下游通路。

参考文献

[1]. Hohnholt MC, et al. The tricarboxylic acid cycle activity in cultured primary astrocytes is strongly accelerated by the protein tyrosine kinase inhibitor tyrphostin 23. Neurochem Int. 2017 Jan;102:13-21.

[2]. Nanzer AM, et al. Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway. Eur J Endocrinol. 2004 Aug;151(2):233-40.

冰袋运输。粉末直接保存于-20℃，有效期2年。溶于DMSO。建议分装后-20℃避光保存，避免反复冻融。