Recombinant Human IgE Protein,His Tag
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产品介绍
Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.
产品性质
产品特色
高活性、高纯度、低内毒素、高稳定性
应用案例
ELISA Data 1:Immobilized Human Fc epsilon RI alpha, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Human IgE, His Tag with the EC50 of 2.5ng/ml determined by ELISA.
ELISA Data 2:Immobilized Human IgE, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Omalizumab, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA.
存储条件
-25~-15℃保存，收到货之日起，有效期1年。复溶后， -85~-65℃保存，3个月有效期。避免反复冻融。
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