Domagrozumab是一种靶向肌生成抑制素的人源化单克隆抗体，其对人类肌生成抑制素具有极高的亲和力。

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粉末-25~-15℃保存，有效期3年；溶于溶剂，-85~-65℃保存，有效期2年。

[1] St Andre M, Johnson M, Bansal PN, Wellen J, Robertson A, Opsahl A, Burch PM, Bialek P, Morris C, Owens J. A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys. Skelet Muscle. 2017 Nov 9;7(1):25. doi: 10.1186/s13395-017-0141-y. PMID: 29121992; PMCID: PMC5679155.