重组人IL-4Rα蛋白 Recombinant Human IL-4R alpha Protein,mFc Tag（94074ES）

Interleukin4 (IL4) is a cytokine with several important functions in the immune system. It primarily helps activate B cells and produce antibodies, especially IgE antibodies related to allergies. It also promotes the differentiation of T helper cells into Th2 cells, supporting humoral immune responses. Additionally, IL4 can help suppress inflammation in certain situations, maintaining immune balance. It is mainly secreted by activated T cells, mast cells, and basophils, and serves as a key target for interventions in various diseases, including allergies and asthma. Due to its crucial role in immune regulation, IL4 has been a significant focus in immunology research.

The IL4RA protein, also known as the interleukin-4 receptor alpha chain, is an important cell surface receptor primarily involved in regulating the immune system. When it binds with interleukin-4 (IL-4), it triggers signaling pathways that promote T cell differentiation and B cell proliferation. IL4RA plays a significant role in allergic reactions and asthma, and its gene polymorphisms are associated with susceptibility to various immune-related diseases.

高纯度、高活性、低内毒素、高批间一致性

SDS-PAGE

Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA

Figure 2.Human IL-4R alpha Protein; mFc Tag was immobilized at 5 μg/ml (100 μL/well). Increasing concentrations of Anti-IL-4R hIgG1 Antibody were added.

-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。