Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.

Western

Western blot analysis of 14-3-3 alpha + beta in Hela lysates using 14-3-3 alpha/beta antibody.