Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.

Western

Western blot analysis of CBS in mouse pancreas and Human fetal liver lysates using CBS antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human liver cancer using CBS antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.