Also acts as a tumor suppressor.MiscellaneousThere are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors .

Western

Western blot analysis of FH/Fumarase in 3T3, Raw264.7 lysates using FH antibody.

Western

Western blot analysis of FH/Fumarase in Jurkat, rat Brain, C6, CHO-K1 lysates using FH/Fumarase antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human tonsil using FH antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry

Immunocytochemistry analysis of FH (green) in Hela using FH antibody,and DAPI(blue).