Stearyl-CoA desaturase that utilizes O2 and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation . Plays an important role in body energy homeostasis . Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides .

稀释比 WB:1/500-1/1000; IHC: 1/50-1/100; IF:1/50-1/200; IP:1/20;

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产品数据
Western blot

Western blot analysis of SCD1 in HeLa lysates using SCD1 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using SCD1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry

Immunocytochemistry analysis of SCD1(green) in HeLa using SCD1 antibody, and DAPI(blue).

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