分子生物学
IVD分子诊断
细胞培养与分析
蛋白研究
细胞因子
重组蛋白
抗体
高通量测序建库
病原检测UCF系列
生物医药
工具酶
抑制剂激活剂与常用试剂
仪器
耗材
Recombinant Mouse MDL-1/CLEC5A Protein,His Tag
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产品介绍

In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.

产品性质
产品特色

高纯度、高活性、低内毒素、高批间一致性

应用案例

SDS-PAGE

Mouse MDL-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

存储条件

-85 ~ -65℃保存,收到货之后有效期1年。
避免反复冻融,打开小瓶前先离心。建议等分分装为一次实验使用量,分装后,-80℃冻存。

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