Metoclopramide通过拮抗5-HT3和D2受体,可用于研究恶心呕吐、胃食管反流及胃轻瘫。
|
英文别名 (English Synonym) |
Metoclopramide |
|
中文名称 (Chinese Name) |
胃复安 |
|
靶点 (Target) |
Dopamine Receptor |
|
通路 (Pathway) |
Neuroscience |
|
CAS号 (CAS NO.) |
364-62-5 |
|
分子式 (Formula) |
C14H22ClN3O2 |
|
分子量 (Molecular Weight) |
299.8 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Edwards CR, Al-Dujaili EA, Boscaro M, Quyyumi S, Miall PA, Rees LH. In vivo and in vitro studies on the effect of metoclopramide on aldosterone secretion. Clin Endocrinol (Oxf). 1980 Jul,13(1):45-50. doi: 10.1111/j.1365-2265.1980.tb01021.x. PMID: 7438463.[2]Gomes RC, Verna C, Simões RS, Wolff RB, Baracat EC, Soares JM Jr. Effects of metoclopramide on the mouse anterior pituitary during the estrous cycle. Clinics (Sao Paulo). 2011,66(6):1101-4. doi: 10.1590/s1807-59322011000600031. Erratum in: Clinics (Sao Paulo). 2011,66(8):1511. Teixeira, Regina Célia Gomes [corrected to Teixeira Gomes, Regina Célia]. PMID: 21808883, PMCID: PMC3129948.
