Meclofenamic acid sodium作为非甾体抗炎药(NSAID)，兼具非选择性缝隙连接阻断剂与高选择性脂肪肥胖相关酶(FTO)抑制剂属性，具有抗炎及抗肿瘤活性。
| 英文别名 (English Synonym) | Meclofenamic acid sodium |
| 中文名称 (Chinese Name) | 甲氯灭酸钠 |
| 靶点 (Target) | COX |
| 通路 (Pathway) | Neuroscience |
| CAS号 (CAS NO.) | 6385-02-0 |
| 分子式 (Formula) | C14H11Cl2NO2·Na |
| 分子量 (Molecular Weight) | 318.13 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存，有效期3年
[1] Schober W, Kehlbach R, Gebert R, Wiskirchen J, Rodegerdts E, Claussen CD, Duda SH. Meclofenamic acid for inhibition of human vascular smooth muscle cell proliferation and migration: an in vitro study. Cardiovasc Intervent Radiol. 2002 Jan-Feb;25(1):57-63. doi: 10.1007/s00270-001-0077-8. Epub 2002 Jan 17. PMID: 11907776.
[2] Chen H, Jia B, Zhang Q, Zhang Y. Meclofenamic Acid Restores Gefinitib Sensitivity by Downregulating Breast Cancer Resistance Protein and Multidrug Resistance Protein 7 via FTO/m6A-Demethylation/c-Myc in Non-Small Cell Lung Cancer. Front Oncol. 2022 Apr 21;12:870636. doi: 10.3389/fonc.2022.870636. PMID: 35530301; PMCID: PMC9069108.
