依巴斯汀（LAS-W 090）是一种口服有效的第二代组胺H1受体拮抗剂，可用于过敏性鼻炎和慢性特发性荨麻疹的相关研究。
|
英文别名 (English Synonym) |
Ebastine |
|
中文名称 (Chinese Name) |
依巴斯汀 |
|
靶点 (Target) |
Histamine Receptor |
|
通路 (Pathway) |
Neuroscience |
|
CAS号 (CAS NO.) |
90729-43-4 |
|
分子式 (Formula) |
C32H39NO2 |
|
分子量 (Molecular Weight) |
469.66 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Tsai FM, Li CH, Wang LK, Chen ML, Lee MC, Lin YY, Wang CH. Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation. Biomed Res Int. 2019 Feb 11;2019:6360503. doi: 10.1155/2019/6360503. PMID: 30886861; PMCID: PMC6388311.[2]Fujii T, Matsumoto S, Amejima H, Hatoyama T, Nakao M, Kagemoto A, Tanaka K, Miyazaki H. Absorption, distribution, metabolism and excretion of [14C]ebastine after a single administration in rats. Arzneimittelforschung. 1994 Apr;44(4):527-38. PMID: 7912071.
