Pimobendan
产品介绍
Pimobendan是磷酸二酯酶III(PDE3)选择性抑制剂。
产品性质
产品特色
| 英文别名 (English Synonym) | Pimobendan |
| 中文名称 (Chinese Name) | 匹莫苯丹 |
| 靶点 (Target) | PDE |
| 通路 (Pathway) | Protease/Metabolic Enzyme |
| CAS号 (CAS NO.) | 74150-27-9 |
| 分子式 (Formula) | C19H18N4O2 |
| 分子量 (Molecular Weight) | 334.37 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
存储条件
-25~-15℃保存，有效期3年
COA
已发表文献
[1] Kajimoto K, Hagiwara N, Kasanuki H, Hosoda S. Contribution of phosphodiesterase isozymes to the regulation of the L-type calcium current in human cardiac myocytes. Br J Pharmacol. 1997 Aug;121(8):1549-56. doi: 10.1038/sj.bjp.0701297. PMID: 9283687; PMCID: PMC1564856.[2]Iwasaki A, Matsumori A, Yamada T, Shioi T, Wang W, Ono K, Nishio R, Okada M, Sasayama S. Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric oxide synthase in a murine model of viral myocarditis. J Am Coll Cardiol. 1999 Apr;33(5):1400-7. doi: 10.1016/s0735-1097(98)00692-5. PMID: 10193745.
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