Plinabulin，又称普那布林，是一种血管破坏剂，通过结合微管蛋白的秋水仙碱结合位点阻止微管蛋白解聚，从而破坏肿瘤血管系统，具有潜在的抗肿瘤活性。

参考文献

[1] Nicholson B, Lloyd GK, Miller BR, et al. NPI-2358 is a tubulin-depolymerizing agent: in-vitro evidence for activity as a tumor vascular-disrupting agent. Anticancer Drugs. 2006 Jan;17(1):25-31. doi: 10.1097/01.cad.0000182745.01612.8a(IF:1.801).

[2] Singh AV, Bandi M, Raje N, et al. A novel vascular disrupting agent plinabulin triggers JNK-mediated apoptosis and inhibits angiogenesis in multiple myeloma cells. Blood. 2011 May 26;117(21):5692-700. doi: 10.1182/blood-2010-12-323857(IF:16.562).

-25~-15℃保存，有效期3年。