Vadadustat是可口服的缺氧诱导因子脯氨酰羟化酶(HIF-PH)抑制剂，是一种促红细胞生成剂，刺激红细胞的产生并改善向组织的氧气输送，临床上用于治疗慢性肾脏病(CKD)相关贫血。

参考文献

[1] Pergola PE, Spinowitz BS, Hartman CS, et al. Vadadustat, a novel oral HIF stabilizer, provides effective anemia treatment in nondialysis-dependent chronic kidney disease. Kidney Int. 2016 Nov;90(5):1115-1122. doi: 10.1016/j.kint.2016.07.019(IF:8.306).

[2] Gupta N, Wish JB. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors: A Potential New Treatment for Anemia in Patients With CKD. Am J Kidney Dis. 2017 Jun;69(6):815-826. doi: 10.1053/j.ajkd.2016.12.011(IF:6.653).

-25~-15℃保存，有效期3年。