Pentostatin 喷司他丁 腺苷脱氨酶(ADA)抑制剂，|CAS 53910-25-1（54529ES）

Pentostatin，又称喷司他丁，是腺苷脱氨酶(ADA)抑制剂，是核苷类似物，具有免疫抑制活性，可用于治疗对α-干扰素治疗无效的毛细胞白血病。腺苷脱氨酶是嘌呤回收所必需的关键酶。

参考文献

[1] Kane BJ, Kuhn JG, Roush MK. Pentostatin: an adenosine deaminase inhibitor for the treatment of hairy cell leukemia. Ann Pharmacother. 1992 Jul-Aug;26(7-8):939-47. doi: 10.1177/106002809202600718 (IF:2.443).

[2] Bethge WA, Kerbauy FR, Santos EB, et al. Extracorporeal photopheresis combined with pentostatin in the conditioning regimen for canine hematopoietic cell transplantation does not prevent GVHD. Bone Marrow Transplant. 2014 Sep;49(9):1198-204. doi: 10.1038/bmt.2014.137(IF:4.674).

[3] Dalla Rosa L, da Silva AS, da Silva AS, et al. Cordycepin (3'-deoxyadenosine) pentostatin (deoxycoformycin) combination treatment of mice experimentally infected with Trypanosoma evansi. Parasitology. 2013 Apr;140(5):663-71. doi: 10.1017/S0031182012001990 (IF:2.456).

-25~-15℃保存，有效期3年。