Cinacalcet hydrochloride (AMG-073 hydrochloride, Cinacalcet HCl, AMG-073 HCl)，又称盐酸西那卡塞，是可口服的Ca receptor (CaR)激动剂，是一种拟钙剂，通过增加甲状旁腺钙敏感受体(CaR)对细胞外钙离子的敏感性而减少甲状旁腺素(PTH)的合成和分泌，临床上用于治疗甲状旁腺功能亢进。

参考文献

[1] Ureña P, et al. Calcimimetic agents: review and perspectives. Kidney Int Suppl. 2003 Jun;(85):S91-6.

[2] D.A. Bushinsky, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92.

[3] Colloton M, et al. Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism. Kidney Int. 2005 Feb;67(2):467-76.

冰袋运输。粉末直接保存于-25~-15℃，有效期3年。建议分装后-25~-15℃干燥保存，避免反复冻融。