Carvedilol (BM-14190, SKF 105517, BM14190, SKF105517),又称卡维地洛或卡维地罗,是可口服的、非选择性β/α-1受体阻断剂,具有扩张血管和降压的作用,临床可用于原发性高血压及心绞痛。
参考文献
[1] Yue TL, et, al. Carvedilol, a new vasodilator and beta adrenoceptor antagonist, is an antioxidant and free radical scavenger. J Pharmacol Exp Ther. 1992 Oct;263(1):92-8.
[2] Ohlstein E H, et al. Carvedilol, a cardiovascular drug, prevents vascular smooth muscle cell proliferation, migration, and neointimal formation following vascular injury. Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6189-93.
[3] Feuerstein GZ, et al. Myocardial protection by the novel vasodilating beta-blocker, carvedilol: potential relevance of anti-oxidant activity. J Hypertens Suppl. 1993 Jun;11(4):S41-8.
冰袋运输。粉末直接保存于-25~-15℃,有效期3年。建议溶解分装后于-25~-15℃干燥保存,避免反复冻融。