Benztropine mesylate (Benzatropine mesylate, Benztropine methanesulfonate, Cogentin mesylate)，又称甲磺酸苯扎托品或甲磺酰苯扎托品，是具有口服活性的多巴胺转运蛋白(DAT)抑制剂，IC₅₀为118 nM，是抗组胺剂，抑制多巴胺的吸收，可用于帕金森氏病的研究。

参考文献

[1] Simoni D, et al. Synthesis and pharmacology of 6-substituted benztropines: discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter. J Med Chem. 2005 May 5;48(9):3337-43.

[2] Jihong Cui, et al. New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate. Oncotarget. 2017 Jan 3;8(1):1007-1022.

[3] Santosh S Kulkarni, et al. Comparative structure-activity relationships of benztropine analogues at the dopamine transporter and histamine H(1) receptors. Bioorg Med Chem. 2006 Jun 1;14(11):3625-34.

冰袋运输。粉末直接保存于-25~-15℃，有效期3年。建议分装后-25~-15℃干燥保存，避免反复冻融。