AR-42 (OSU-HDAC42, HDAC-42, AR42)是HDAC抑制剂，IC₅₀为30 nM，对多种肿瘤具有有效的抗肿瘤活性。AR-42能诱导细胞生长抑制，细胞周期阻滞，细胞凋亡。

参考文献

[1] Lu Q, et al. Structure-based optimization of phenylbutyrate-derived histone deacetylase inhibitors. J Med Chem. 2005 Aug 25;48(17):5530-5.

[2] Sargeant AM, et al. OSU-HDAC42, a histone deacetylase inhibitor, blocks prostate tumor progression in the transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2008 May 15;68(10):3999-4009.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。