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Anti-ERBB1/EGFR/HER1 Reference Antibody (depatuxizumab)
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Depatuxizumab 是一种可透过血脑屏障 (brain-penetrant) 的人源化肿瘤特异性抗 EGFR 的单克隆抗体。Depatuxizumab 抑制突变型 EGFRvIII 和野生型 EGFR 异种移植瘤模型的生长。Depatuxizumab 可用于癌症研究。
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For Powder, reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
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Anti-ERBB1 / EGFR / HER1 Reference Antibody (depatuxizumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

The purity of Anti-ERBB1 / EGFR / HER1 Reference Antibody (depatuxizumab) is 99.58%, determined by SEC-HPLC.

Human ERBB1 / EGFR / HER1, His Tag at 2 μg/mL can bind Depatuxizumab ,EC50=0.01559 μg/mL.

Human EGFR CHO-K cells were stained with Anti-ERBB1 / EGFR / HER1 Reference Antibody (depatuxizumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=34.40 nM.

存储条件
-80°C for 2 years under sterile conditions;-20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
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