Guselkumab 是一种人源化 IgG1 单克隆抗体，可特异性靶向 IL-23 的 p19 亚基，通过阻断 IL-23 介导的信号转导，Guselkumab 能够有效抑制下游细胞因子的产生，适用于银屑病关节炎的相关机制研究。

Purity:SDS-PAGE

Anti-IL-23 Reference Antibody (guselkumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

Purity:SEC-HPLC

The purity of Anti-IL-23 Reference Antibody (guselkumab) is 98.97%, determined by SEC-HPLC.

Bioactivity:ELISA

Immobilized human IL 23P40 His at 2 ug/mL can bind Anti-IL-23 Reference Antibody (guselkumab), EC50=0.009014 ug/mL.

Function:Luciferase

Anti-IL-23 Reference Antibody (guselkumab) induced report gene STAT3 activity was evaluated using Human IL23 HEK-Blue. The EC50 was approximately 0.0095 ug/mL.

-25~-15℃保存，有效期1年。