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Anti-CEACAM5/CEA/CD66e Reference Antibody (Tusamitamab ravtansine)
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Tusamitamab ravtansine (SAR408701) 是一种针对表达 CEACAM5 的肿瘤细胞的靶向 ADC,由人源化抗 CEACAM5 单克隆抗体组成,通过可裂解接头与强效细胞毒性剂美登木素生物碱 DM4 共价连接。Tusamitamab ravtansine 的平均药物抗体比 (DAR) 为 3.8。
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For Powder, reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
应用案例

本产品仅用作科学研究!


The purity of Anti-CEACAM5 / CEA / CD66e Reference Antibody (tusamitamab ravtansine) is 100%, determined by SEC-HPLC.

Immobilized human HER2(23 652) His at 2 ug/mL can bind Anti-CEACAM5 / CEA / CD66e Reference Antibody (Tusamitamab ravtansine), EC50 is 0.003203 ug/mL.

Human CEACAM5 / CEA / CD66e HEK293 Cell Line were stained Anti-CEACAM5 / CEA / CD66e Reference Antibody (Tusamitamab ravtansine) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, The EC50 is 0.61 ug/mL.

存储条件
-80°C for 2 years under sterile conditions;-20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
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