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Anti-ERBB1/EGFR/HER1 Reference Antibody (depatuxizumab-MMAF)
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Depatuxizumab 是一种可透过血脑屏障 (brain-penetrant) 的人源化肿瘤特异性抗 EGFR 的单克隆抗体。Depatuxizumab 抑制突变型 EGFRvIII 和野生型 EGFR 异种移植瘤模型的生长。Depatuxizumab 可用于癌症研究。
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For Powder, reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
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本产品仅用作科学研究!


Anti-ERBB1 / EGFR / HER1 Reference Antibody (depatuxizumab-MMAF) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 90%.

The purity of Anti-ERBB1 / EGFR / HER1 Reference Antibody (depatuxizumab-MMAF) is 98.38%, determined by SEC-HPLC.

Immobilized EGFR-P00533-25-645-chis at 2 μg/mL (30 μL/well) can bind Anti-ERBB1 / EGFR / HER1 Reference Antibody (depatuxizumab-MMAF) with the EC50 of 19.05 ng/mL.

The drug-to-antibody ratio (DAR) of the Anti-ERBB1 / EGFR / HER1 Reference Antibody (depatuxizumab-MMAF) is 4.3.

存储条件
-80°C for 2 years under sterile conditions;-20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
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